
Problem Unit #4
Lecture #7
You can click on the link to listen to a RealAudio file of
the day's lecture. The following description contains the material
discussed and the source of the overheads used during the presentation.
- Code:
- D = Devlin (Textbook of Biochemistry with Clinical Correlations)
- ECN = Created by me
- MV = Mathews & van Holde (Biochemistry)
- VV = Voet & Voet (Biochemistry)
Lecture 7 (1/6/00) 45
minutes
- Announcements
- Remember to check the Web site for
updates to the Study Guide
- Metabolism
at a Glance by J. G. Salway is available
for $29.95 and is an excellent approach to the metabolism covered
in the Problem Units. Blackwell Science Inc. has other titles
in their "at a Glance" series.
- Lecture #6 review
- Sugar interconversions
- Biosynthesis of complex carbohydrates
- Glycoproteins
- Proteoglycans
- Energy producing and energy utilizing
systems
- ATP, GTP, CTP, UTP in biosynthesis
(D Figs 6.01, 6.02, 6.03, 6.04)
- Conversion of 2 ADP Æ AMP + ATP
(D Fig 6.05)
- Thermodynamics and energy-rich components
- Free energy, oxidized and reduced organic molecules
(D Fig 6.06)
- High-energy bonds (D Figs 6.07,
6.08, 6.09)
- Sources and fates of acetyl-coenzyme
A
- Precursors and structure of acetyl-coenzyme
A (D Figs 6.10, 6.11)
- Sources and fates of pyruvate (D
Fig 6.12)
- Pyruvate dehydrogenase complex, coenzymes
(D Figs 6.14a, 6.14b, 6.14c, 6.14d, 6.15)
- Regulatory features of pyruvate dehydrogenase
complex, kinase and phosphatase, hormones (D Fig 6.16)
- Sources and fates of acetyl-coenzyme
A (D Fig 6.17)
- Tricarboxylic acid cycle
- Overview of substrates, products and
reactions (D Figs 6.18, 6.19,
6.20, 6.21)
- Regulatory features of citric acid
cycle (D Figs 6.22, 6.23)
- Preview of lecture #8
- Mitochondrial electron transport chain
and shuttles
Remember to look over the Study Guide and textbook sections
for additional illustrations that may assist in your understanding
of the presented material.
PU04
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